Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan
The plants of genus Cymbopogon are well known for their use in traditional medicine and for their high content of essential oils that are widely used as flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils isolated from the dried stems and inflorescence of cultivated...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
University of Belgrade, University of Novi Sad
2017-01-01
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Series: | Archives of Biological Sciences |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600113P.pdf |
Summary: | The plants of genus Cymbopogon are well known for their use in traditional
medicine and for their high content of essential oils that are widely used as
flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils
isolated from the dried stems and inflorescence of cultivated Cymbopogon
schoenanthus (L.) Spreng. (Poaceae) collected from Khartoum state (Sudan) in
two periods were studied. The results of chemical analysis of C. schoenanthus
revealed that this plant is rich in essential oil which is a valuable source
of the commercially important monoterpene, piperitone (47.7-71.5%). Other
abundant constituents of the oils were intermedeol (6.1-17.3%), δ-2-carene
(4.5-10.0%) and elemol (2.7-9.0%). The essential oil from the inflorescence
was tested for spasmolytic activity using three different experimental
models: against spontaneous contractions, contractions induced with
acetylcholine and contractions induced with potassium chloride. The oil
exhibited strong, significant and dose-dependent spasmolytic activity,
indicating the possibility for further investigations of this essential oil
for its medicinal purposes or application in food industry. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no.173021 and Grant no. III41018] |
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ISSN: | 0354-4664 1821-4339 |