Let me infuse this for you – A way to solve the first YPIC challenge
In a common proteomics analysis today, the origins of our sample in the vial are known and therefore a database dependent approach to identify the containing peptides can be used. The first YPIC challenge though provided us with 19 synthetic peptides, which together formed an English sentence. For t...
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doaj-6fce0458792b40ee827d9feab9b053992020-11-25T01:35:07ZengElsevierEuPA Open Proteomics2212-96852019-03-01221921Let me infuse this for you – A way to solve the first YPIC challengeBritta Eggers0Sandra Pacharra1Martin Eisenacher2Katrin Marcus3Julian Uszkoreit, Dr.4Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Gesundheitscampus 4, D-44801, Bochum, GermanyRuhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Gesundheitscampus 4, D-44801, Bochum, GermanyRuhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Gesundheitscampus 4, D-44801, Bochum, GermanyRuhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Gesundheitscampus 4, D-44801, Bochum, GermanyCorresponding author.; Ruhr University Bochum, Faculty of Medicine, Medizinisches Proteom-Center, Gesundheitscampus 4, D-44801, Bochum, GermanyIn a common proteomics analysis today, the origins of our sample in the vial are known and therefore a database dependent approach to identify the containing peptides can be used. The first YPIC challenge though provided us with 19 synthetic peptides, which together formed an English sentence. For the identification of these peptides, a de-novo approach was used, which brought us together with an internet search engine to the hidden sentence. But only having the sentence was not sufficient for us, we also wanted to identify as many as possible of the spectra in our data. Therefore, we created and refined a database approach from the de-novo method and finally could identify the peptide-sentence with a good overlap.http://www.sciencedirect.com/science/article/pii/S2212968519300108 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Britta Eggers Sandra Pacharra Martin Eisenacher Katrin Marcus Julian Uszkoreit, Dr. |
spellingShingle |
Britta Eggers Sandra Pacharra Martin Eisenacher Katrin Marcus Julian Uszkoreit, Dr. Let me infuse this for you – A way to solve the first YPIC challenge EuPA Open Proteomics |
author_facet |
Britta Eggers Sandra Pacharra Martin Eisenacher Katrin Marcus Julian Uszkoreit, Dr. |
author_sort |
Britta Eggers |
title |
Let me infuse this for you – A way to solve the first YPIC challenge |
title_short |
Let me infuse this for you – A way to solve the first YPIC challenge |
title_full |
Let me infuse this for you – A way to solve the first YPIC challenge |
title_fullStr |
Let me infuse this for you – A way to solve the first YPIC challenge |
title_full_unstemmed |
Let me infuse this for you – A way to solve the first YPIC challenge |
title_sort |
let me infuse this for you – a way to solve the first ypic challenge |
publisher |
Elsevier |
series |
EuPA Open Proteomics |
issn |
2212-9685 |
publishDate |
2019-03-01 |
description |
In a common proteomics analysis today, the origins of our sample in the vial are known and therefore a database dependent approach to identify the containing peptides can be used. The first YPIC challenge though provided us with 19 synthetic peptides, which together formed an English sentence. For the identification of these peptides, a de-novo approach was used, which brought us together with an internet search engine to the hidden sentence. But only having the sentence was not sufficient for us, we also wanted to identify as many as possible of the spectra in our data. Therefore, we created and refined a database approach from the de-novo method and finally could identify the peptide-sentence with a good overlap. |
url |
http://www.sciencedirect.com/science/article/pii/S2212968519300108 |
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