Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on whole blood coagulation and platelet function in dogs with suspected intracranial hypertension - a pilot study

Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on whole blood coagulation and platelet function in dogs with suspected intracranial hypertension - a pilot study

Abstract Background Hyperosmolar therapy with either mannitol or hypertonic saline (HTS) is commonly used in the treatment of intracranial hypertension (ICH). In vitro data indicate that both mannitol and HTS affect coagulation and platelet function in dogs. The aim of this study was to compare the...

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Bibliographic Details
Main Authors: Ivayla D. Yozova, Judith Howard, Diana Henke, Daniel Dirkmann, Katja N. Adamik
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Veterinary Research
Subjects:
Intracranial hypertension
Osmotherapy
Hypertonic saline
Mannitol
Hemostasis
Thromboelastometry
Online Access:http://link.springer.com/article/10.1186/s12917-017-1108-2

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http://link.springer.com/article/10.1186/s12917-017-1108-2

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