The bi-functional organization of human basement membranes.

The current basement membrane (BM) model proposes a single-layered extracellular matrix (ECM) sheet that is predominantly composed of laminins, collagen IVs and proteoglycans. The present data show that BM proteins and their domains are asymmetrically organized providing human BMs with side-specific...

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Bibliographic Details
Main Authors: Willi Halfter, Christophe Monnier, David Müller, Philipp Oertle, Guy Uechi, Manimalha Balasubramani, Farhad Safi, Roderick Lim, Marko Loparic, Paul Bernhard Henrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3700973?pdf=render