Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus

Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus

As a key anti-inflammatory cytokine, IL-10 is crucial in preventing inflammatory and autoimmune diseases. However, in human and murine lupus, its role remains controversial. Our aim was to understand regulation and immunologic effects of IL-10 on different immune functions in the setting of lupus. T...

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Bibliographic Details
Main Authors: Anaïs Amend, Natalie Wickli, Anna-Lena Schäfer, Dalina T. L. Sprenger, Rudolf A. Manz, Reinhard E. Voll, Nina Chevalier
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
IL-10
systemic lupus erythematosus
IL-10R
autoimmunity
Online Access:https://www.mdpi.com/1422-0067/22/3/1347

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