Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cells[S]
Pulmonary artery endothelial plexiform lesion is responsible for pulmonary vascular remodeling (PVR), a basic pathological change of pulmonary arterial hypertension (PAH). Recent evidence suggests that epoxyeicosatrienoic acid (EET), which is derived from arachidonic acid by cytochrome p450 (CYP) ep...
Main Authors: | Jun Ma, Lei Zhang, Weina Han, Tingting Shen, Cui Ma, Yun Liu, Xiaowei Nie, Mengmeng Liu, Yajuan Ran, Daling Zhu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-06-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520317028 |
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