Studying the Endothelial Glycocalyx in vitro: What Is Missing?

Studying the Endothelial Glycocalyx in vitro: What Is Missing?

All human cells are coated by a surface layer of proteoglycans, glycosaminoglycans (GAGs) and plasma proteins, called the glycocalyx. The glycocalyx transmits shear stress to the cytoskeleton of endothelial cells, maintains a selective permeability barrier, and modulates adhesion of blood leukocytes...

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Bibliographic Details
Main Authors: Andrew B. Haymet, Nicole Bartnikowski, Emily S. Wood, Michael P. Vallely, Angela McBride, Sophie Yacoub, Scott B. Biering, Eva Harris, Jacky Y. Suen, John F. Fraser
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
endothelium
glycocalyx
vasculopathy
vascular
endothelial surface layer
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.647086/full

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