Genomic Analysis of Hepatitis B Virus Reveals Antigen State and Genotype as Sources of Evolutionary Rate Variation

Genomic Analysis of Hepatitis B Virus Reveals Antigen State and Genotype as Sources of Evolutionary Rate Variation

Hepatitis B virus (HBV) genomes are small, semi-double-stranded DNA circular genomes that contain alternating overlapping reading frames and replicate through an RNA intermediary phase. This complex biology has presented a challenge to estimating an evolutionary rate for HBV, leading to difficulties...

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Bibliographic Details
Main Authors: Andrew Rambaut, Beth Shapiro, Burentau Teriboriki, Tebuka Toatu, David Penny, Andrew Masta, Joji Malani, Mathias Supuri, Jan Pryor, Abby Harrison, Philippe Lemey, Chris Moyes, Susanne Horn, Matthew Hurles
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Viruses
Subjects:
hepatitis B virus
molecular clock
Bayesian phylogenetics
Online Access:http://www.mdpi.com/1999-4915/3/2/83/

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