The Regulation of Rab GTPases by Phosphorylation
Rab proteins are small GTPases that act as molecular switches for intracellular vesicle trafficking. Although their function is mainly regulated by regulatory proteins such as GTPase-activating proteins and guanine nucleotide exchange factors, recent studies have shown that some Rab proteins are phy...
Main Authors: | Lejia Xu, Yuki Nagai, Yotaro Kajihara, Genta Ito, Taisuke Tomita |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/9/1340 |
Similar Items
-
The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System
by: Tomoki Kuwahara, et al.
Published: (2020-03-01) -
Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration
by: Ga Ram Jeong, et al.
Published: (2018-02-01) -
Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation
by: Tomoki Kuwahara, et al.
Published: (2020-11-01) -
RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
by: Jesús Madero-Pérez, et al.
Published: (2018-11-01) -
Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
by: Jesús Madero-Pérez, et al.
Published: (2018-01-01)