Associations of Plasma 3-Methylhistidine with Frailty Status in French Cohorts of the FRAILOMIC Initiative

Associations of Plasma 3-Methylhistidine with Frailty Status in French Cohorts of the FRAILOMIC Initiative

Frailty and sarcopenia are characterized by a loss of muscle mass and functionality and are diagnosed mainly by functional tests and imaging parameters. However, more muscle specific biomarkers are needed to improve frailty diagnosis. Plasma 3-methylhistidine (3-MH), as well as the 3-MH-to-creatinin...

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Bibliographic Details
Main Authors: Bastian Kochlik, Wolfgang Stuetz, Karine Pérès, Catherine Féart, Jesper Tegner, Leocadio Rodriguez-Mañas, Tilman Grune, Daniela Weber
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Journal of Clinical Medicine
Subjects:
frailty
aging
methylhistidine
biomarker
human study
muscle protein turnover
Online Access:https://www.mdpi.com/2077-0383/8/7/1010

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