Roles of Primary Cilia in the Developing Brain

Roles of Primary Cilia in the Developing Brain

Essential to development, primary cilia are microtubule-based cellular organelles that protrude from the surface of cells. Acting as cellular antenna, primary cilia play central roles in transducing or regulating several signaling pathways, including Sonic hedgehog (Shh) and Wnt signaling. Defects i...

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Bibliographic Details
Main Authors: Sang Min Park, Hee Jin Jang, Jeong Ho Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
primary cilia
Wnt
MTOR
autophagy
ciliopathy
FMCD
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00218/full

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