The Selective HDAC6 Inhibitor ACY-738 Impacts Memory and Disease Regulation in an Animal Model of Multiple Sclerosis

The Selective HDAC6 Inhibitor ACY-738 Impacts Memory and Disease Regulation in an Animal Model of Multiple Sclerosis

Multiple sclerosis (MS) is a complex disease characterized by autoimmune demyelination and progressive neurodegeneration. Pathogenetic mechanisms of the disease remain largely unknown. Changes in synaptic functions have been reported; however, the significance of such alterations in the disease cour...

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Bibliographic Details
Main Author: Patrizia LoPresti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
drug therapy
memory
neurodegeneration
disability
CNS repair
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00519/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00519/full

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