ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis

Abstract Background ANXA2 (Annexin A2) is a pleiotropic calcium-dependent phospholipid binding protein that is abnormally expressed in various cancers. We previously found that ANXA2 is upregulated in esophageal squamous cell carcinoma (ESCC). This study was designed to investigate the functional si...

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Bibliographic Details
Main Authors: Sai Ma, Chen-Chen Lu, Li-Yan Yang, Juan-Juan Wang, Bo-Shi Wang, Hong-Qing Cai, Jia-Jie Hao, Xin Xu, Yan Cai, Yu Zhang, Ming-Rong Wang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Esophageal squamous cell carcinoma
Annexin A2
Invasion
Metastasis
VEGF
Online Access:http://link.springer.com/article/10.1186/s13046-018-0851-y

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