Alterations of Astrocytes in the Context of Schizophrenic Dementia

Alterations of Astrocytes in the Context of Schizophrenic Dementia

The levels of the astrocyte markers (GFAP, S100B) were increased unevenly in patients with schizophrenia. Reactive astrogliosis was found in approximately 70% of patients with schizophrenia. The astrocytes play a major role in etiology and pathogenesis of schizophrenia. Astrocytes produce the compon...

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Bibliographic Details
Main Authors: Vadim V. Tarasov, Andrey A. Svistunov, Vladimir N. Chubarev, Susanna S. Sologova, Polina Mukhortova, Dmitrii Levushkin, Siva G. Somasundaram, Cecil E. Kirkland, Sergey O. Bachurin, Gjumrakch Aliev
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
schizophrenia
astrocyte
N-methyl-d-aspartate
glutamate
glial fibrillary acidic protein
S100B
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01612/full

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