Programmed death ligand 1 (PD-L1) expression influences the immune-tolerogenic microenvironment in antiretroviral therapy-refractory Kaposi's sarcoma: A pilot study

Programmed death ligand 1 (PD-L1) expression influences the immune-tolerogenic microenvironment in antiretroviral therapy-refractory Kaposi's sarcoma: A pilot study

Upregulation of programmed death ligand 1 (PD-L1) is a mechanism of immune escape utilized by a variety of tumors. PD-L1 expression in tumor cells or in the surrounding infiltrate correlates with clinical responsiveness to novel therapies targeting the PD-1/PD-L1 immune checkpoint. In the context of...

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Bibliographic Details
Main Authors: Salvinia Mletzko, David J. Pinato, Rebecca C. Robey, Alessia Dalla Pria, Peter Benson, Nesrina Imami, Mark Bower
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:OncoImmunology
Subjects:
cart
hiv
ks
microenvironment
pd-l1
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1304337

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