Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma

Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma

Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is recognized as a refractory eosinophilic disorder characterized by both upper and lower airway inflammation. In some severe cases, disease control is poor, likely due to local steroid insensitivity....

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Bibliographic Details
Main Authors: Yoshiki Kobayashi, Akira Kanda, Yasutaka Yun, Dan Van Bui, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Hiroshi Iwai
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
asthma
corticosteroid sensitivity
eosinophilic chronic rhinosinusitis
glucocorticoid receptor
protein phosphatase 2a
Online Access:https://www.mdpi.com/2218-273X/10/2/326

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