LIGAND BASED PHARMACOPHORE MODELING AND QSAR ANALYSIS OF HETEROCYCLIC DIAMIDINE DERIVATIVES AS ANTI-PARASITIC DNA MINOR GROOVE BINDERS
Ligand based pharmacophore modelling (LBPM) of a group of 26 heterocyclic diamidine derivatives having clinical bioactivity against Trypanosoma brucei gambiense (TBG). A four point pharmacophore model of anti-parasitic diamidines has been developed. Positive ionic and aromatic features were ident...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
West Bengal Veterinary Alumni Association
2013-12-01
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| Series: | Exploratory Animal and Medical Research |
| Subjects: | |
| Online Access: | http://www.animalmedicalresearch.org/Vol.3_Issue-2_December_2013/Subhadip%20Banerjee.pdf |