Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures
Soil-transmitted helminth (STH) infections are common in the tropical and subtropical countries. The burden of disease is highest in endemic areas with limited access to good quality water supply and poor sanitary conditions. Major approaches to control and reduce morbidity caused by worm infections...
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doaj-70e72c6338a24c0ebf0f7a82a7f17ce22020-11-25T03:11:51ZengMDPI AGTropical Medicine and Infectious Disease2414-63662020-06-015939310.3390/tropicalmed5020093Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control MeasuresMirabeau Mbong Ngwese0Gédéon Prince Manouana1Paul Alvyn Nguema Moure2Michael Ramharter3Meral Esen4Ayola Akim Adégnika5Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP: 242, GabonCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP: 242, GabonCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP: 242, GabonGerman Centre for Infection Research (DZIF), partner site Hamburg-Luebeck-Borstel, D-20359 Hamburg, GermanyInstitut für Tropenmedizin, Eberhad Karls Universität Tübingen, D-72074 Tübingen, GermanyCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP: 242, GabonSoil-transmitted helminth (STH) infections are common in the tropical and subtropical countries. The burden of disease is highest in endemic areas with limited access to good quality water supply and poor sanitary conditions. Major approaches to control and reduce morbidity caused by worm infections include the periodic deworming of pre-school and school-aged children with anthelminthic drugs. Population-based studies and individual patient management including interventional studies can only be successful when accurate diagnostic techniques are used. The lack of appropriate diagnostic tools providing accurate results concerning both infectious status and intensity of infection—as these two factors vary in regions of low infection intensities—is a major challenge. Currently, available techniques show limited sensitivity and specificity and as such, a combination of several techniques is usually used to diagnose the large variety of parasite species. The objective of this review was to describe the advantages and disadvantages of the different available techniques for the diagnosis of STH infections and to highlight their use in control programs.https://www.mdpi.com/2414-6366/5/2/93diagnosticsintestinal helminthssoil-transmitted helminthscontrol measures |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mirabeau Mbong Ngwese Gédéon Prince Manouana Paul Alvyn Nguema Moure Michael Ramharter Meral Esen Ayola Akim Adégnika |
spellingShingle |
Mirabeau Mbong Ngwese Gédéon Prince Manouana Paul Alvyn Nguema Moure Michael Ramharter Meral Esen Ayola Akim Adégnika Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures Tropical Medicine and Infectious Disease diagnostics intestinal helminths soil-transmitted helminths control measures |
author_facet |
Mirabeau Mbong Ngwese Gédéon Prince Manouana Paul Alvyn Nguema Moure Michael Ramharter Meral Esen Ayola Akim Adégnika |
author_sort |
Mirabeau Mbong Ngwese |
title |
Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures |
title_short |
Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures |
title_full |
Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures |
title_fullStr |
Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures |
title_full_unstemmed |
Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures |
title_sort |
diagnostic techniques of soil-transmitted helminths: impact on control measures |
publisher |
MDPI AG |
series |
Tropical Medicine and Infectious Disease |
issn |
2414-6366 |
publishDate |
2020-06-01 |
description |
Soil-transmitted helminth (STH) infections are common in the tropical and subtropical countries. The burden of disease is highest in endemic areas with limited access to good quality water supply and poor sanitary conditions. Major approaches to control and reduce morbidity caused by worm infections include the periodic deworming of pre-school and school-aged children with anthelminthic drugs. Population-based studies and individual patient management including interventional studies can only be successful when accurate diagnostic techniques are used. The lack of appropriate diagnostic tools providing accurate results concerning both infectious status and intensity of infection—as these two factors vary in regions of low infection intensities—is a major challenge. Currently, available techniques show limited sensitivity and specificity and as such, a combination of several techniques is usually used to diagnose the large variety of parasite species. The objective of this review was to describe the advantages and disadvantages of the different available techniques for the diagnosis of STH infections and to highlight their use in control programs. |
topic |
diagnostics intestinal helminths soil-transmitted helminths control measures |
url |
https://www.mdpi.com/2414-6366/5/2/93 |
work_keys_str_mv |
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1724652632702713856 |