Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques
In this study, Marlin et al. provide insights into the potential use of subunit vaccines that induce a high level of protection against SARS-CoV-2 in animal models.
Main Authors: | Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy, Roger Le Grand |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25382-0 |
Similar Items
-
DC Subsets Regulate Humoral Immune Responses by Supporting the Differentiation of Distinct Tfh Cells
by: Aurélie Bouteau, et al.
Published: (2019-05-01) -
TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice.
by: Véronique Godot, et al.
Published: (2020-11-01) -
P19-26. Directing macaque immune responses with an anti-dendritic cell HIV Gag p24 fusion protein vaccine
by: Martinon F, et al.
Published: (2009-10-01) -
Targeting human langerin promotes HIV-1 specific humoral immune responses.
by: Jérôme Kervevan, et al.
Published: (2021-07-01) -
Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo.
by: Anne-Laure Flamar, et al.
Published: (2015-01-01)