Blood–Brain Barrier Dynamic Device with Uniform Shear Stress Distribution for Microscopy and Permeability Measurements

Blood–Brain Barrier Dynamic Device with Uniform Shear Stress Distribution for Microscopy and Permeability Measurements

Neurology has always been one of the therapeutic areas with higher attrition rates. One of the main difficulties is the presence of the blood–brain barrier (BBB) that restricts access to the brain for major drugs. This low success rate has led to an increasing demand for in vitro tools. The shear st...

Full description

Bibliographic Details
Main Authors: Nina Choublier, Yoann Müller, Loris Gomez Baisac, Jeremy Laedermann, Casimir de Rham, Xavier Declèves, Adrien Roux
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Applied Sciences
Subjects:
blood–brain barrier
brain endothelial cell
shear stress
in vitro models
drug development
biological barriers
Online Access:https://www.mdpi.com/2076-3417/11/12/5584

Similar Items

Similar Items