Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature
The autoimmune disease, myasthenia gravis (MG), can mimic a variety of neurological disorders leading to a delay in diagnosis and treatment. On occasions, misdiagnosis of MG could lead to unnecessary and potentially harmful therapeutic interventions. We report on a 12 year-old boy, in whom MG was mi...
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doaj-712aba9a6401418589ff2db266bdac552020-11-24T20:51:58ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal 2075-051X2075-05282012-02-01121103108Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literatureAbdullah Al-Asmi0Ramachandiran Nandhagopal1P C Jacob2Arunodaya Gujjar3Department of Medicine, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Medicine, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, OmanDepartment of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, OmanThe autoimmune disease, myasthenia gravis (MG), can mimic a variety of neurological disorders leading to a delay in diagnosis and treatment. On occasions, misdiagnosis of MG could lead to unnecessary and potentially harmful therapeutic interventions. We report on a 12 year-old boy, in whom MG was mistaken for meningitic sequelae and subsequently for critical neuropathy/myopathy resulting in considerable morbidity for nearly a decade. Subsequent correct diagnosis and optimal management resulted in significant improvement in his functional status. We discuss the importance of considering MG as one of the potential differential diagnoses among cases of recurrent respiratory pump failure, or unexplained bulbar symptoms where documentary proof of the previous diagnoses including work-up for MG is lacking. We also review the literature on MG misdiagnosis and highlight the potential pitfalls in MG diagnosis.http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=157562d5f358efebf08be3ab9e8c76d2Myasthenia gravisBulbar palsyPneumoniaMeningitis sequelaeCase reportOman |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abdullah Al-Asmi Ramachandiran Nandhagopal P C Jacob Arunodaya Gujjar |
spellingShingle |
Abdullah Al-Asmi Ramachandiran Nandhagopal P C Jacob Arunodaya Gujjar Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature Sultan Qaboos University Medical Journal Myasthenia gravis Bulbar palsy Pneumonia Meningitis sequelae Case report Oman |
author_facet |
Abdullah Al-Asmi Ramachandiran Nandhagopal P C Jacob Arunodaya Gujjar |
author_sort |
Abdullah Al-Asmi |
title |
Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature |
title_short |
Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature |
title_full |
Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature |
title_fullStr |
Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature |
title_full_unstemmed |
Misdiagnosis of Myasthenia Gravis and Subsequent Clinical Implication; A case report and review of literature |
title_sort |
misdiagnosis of myasthenia gravis and subsequent clinical implication; a case report and review of literature |
publisher |
Sultan Qaboos University |
series |
Sultan Qaboos University Medical Journal |
issn |
2075-051X 2075-0528 |
publishDate |
2012-02-01 |
description |
The autoimmune disease, myasthenia gravis (MG), can mimic a variety of neurological disorders leading to a delay in diagnosis and treatment. On occasions, misdiagnosis of MG could lead to unnecessary and potentially harmful therapeutic interventions. We report on a 12 year-old boy, in whom MG was mistaken for
meningitic sequelae and subsequently for critical neuropathy/myopathy resulting in considerable morbidity for
nearly a decade. Subsequent correct diagnosis and optimal management resulted in significant improvement in his functional status. We discuss the importance of considering MG as one of the potential differential diagnoses among cases of recurrent respiratory pump failure, or unexplained bulbar symptoms where documentary proof of the previous diagnoses including work-up for MG is lacking. We also review the literature on MG misdiagnosis and highlight the potential pitfalls in MG diagnosis. |
topic |
Myasthenia gravis Bulbar palsy Pneumonia Meningitis sequelae Case report Oman |
url |
http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=157562d5f358efebf08be3ab9e8c76d2 |
work_keys_str_mv |
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