Enterovirus A71 Vaccines

Enterovirus A71 Vaccines

Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A...

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Bibliographic Details
Main Authors: Mei-Ling Li, Shin-Ru Shih, Blanton S. Tolbert, Gary Brewer
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
Enterovirus A71
Hand
foot and mouth disease (HFMD)
Vaccine
Sinovac
Online Access:https://www.mdpi.com/2076-393X/9/3/199
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spelling doaj-7144eea79b2b49138a5c61555ffcf74f2021-02-28T00:03:42ZengMDPI AGVaccines2076-393X2021-02-01919919910.3390/vaccines9030199Enterovirus A71 VaccinesMei-Ling Li0Shin-Ru Shih1Blanton S. Tolbert2Gary Brewer3Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USAResearch Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan 333, TaiwanDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USADepartment of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USAEnterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.https://www.mdpi.com/2076-393X/9/3/199Enterovirus A71Handfoot and mouth disease (HFMD)VaccineSinovac
collection DOAJ
language English
format Article
sources DOAJ
author Mei-Ling Li
Shin-Ru Shih
Blanton S. Tolbert
Gary Brewer
spellingShingle Mei-Ling Li
Shin-Ru Shih
Blanton S. Tolbert
Gary Brewer
Enterovirus A71 Vaccines
Vaccines
Enterovirus A71
Hand
foot and mouth disease (HFMD)
Vaccine
Sinovac
author_facet Mei-Ling Li
Shin-Ru Shih
Blanton S. Tolbert
Gary Brewer
author_sort Mei-Ling Li
title Enterovirus A71 Vaccines
title_short Enterovirus A71 Vaccines
title_full Enterovirus A71 Vaccines
title_fullStr Enterovirus A71 Vaccines
title_full_unstemmed Enterovirus A71 Vaccines
title_sort enterovirus a71 vaccines
publisher MDPI AG
series Vaccines
issn 2076-393X
publishDate 2021-02-01
description Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.
topic Enterovirus A71
Hand
foot and mouth disease (HFMD)
Vaccine
Sinovac
url https://www.mdpi.com/2076-393X/9/3/199
work_keys_str_mv AT meilingli enterovirusa71vaccines
AT shinrushih enterovirusa71vaccines
AT blantonstolbert enterovirusa71vaccines
AT garybrewer enterovirusa71vaccines
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