The Correlation between Body Mass Index and Routine Parameters in Men Over Fifty

• Main Authors: Deok Ha Seo, Sol Yoon, Jae Hwi Choi, Jungmo Do, Sin Woo Lee, Chunwoo Lee, Seong Uk Jeh, See Min Choi, Sung Chul Kam, Jeong Seok Hwa, Ky Hyun Chung, Sung Won Kwon, Sae Chul Kim, Dong Soo Park, Jae Mann Song, Kyung Seop Lee, Jae Seog Hyun
• Format: Article
• Language: English
• Published: Korean Society for Sexual Medicine and Andrology 2017-12-01
• Series: The World Journal of Men's Health
• Subjects: Body mass index; Lower urinary tract symptoms; Prostate-specific antigen; Prostatic hyperplasia
• Online Access: https://www.wjmh.org/Synapse/Data/PDFData/2074WJMH/wjmh-35-178.pdf
• ISSN: 2287-4208; 2287-4690

Purpose: This study aimed to investigate the relationships between body mass index (BMI) and prostate-specific antigen (PSA) levels, international prostate symptom score (IPSS), quality of life (QoL), and prostate volume (PV). Materials and Methods: Height, weight, PSA levels, PV, and IPSS were analyzed in 15,435 patients who underwent a prostate examination between 2001 and 2014. Patients aged ＜50 years or with a PSA level ≥10 ng/mL were excluded. The relationships between BMI and PSA, IPSS, QoL, and PV were analyzed by a scatter plot, one-way analysis of variance, and the Pearson correlation coefficient. Results: The mean age was 71.95±7.63 years, the mean BMI was 23.59±3.08 kg/m2, the mean PSA level was 1.45±1.45 ng/mL, the mean IPSS was 15.53±8.31, the mean QoL score was 3.48±1.25, and the mean PV was 29.72±14.02 mL. PSA, IPSS, and QoL showed a tendency to decrease with increasing BMI, and there were statistically significant differences for each parameter (p≤0.001). PV showed a significant tendency to increase with BMI (p＜0.001). In the correlation analysis, BMI showed a statistically significant correlation (p＜0.001) with PSA, IPSS, and QoL, although the correlations were very weak. In contrast, BMI showed a significant correlation with PV (p＜0.001), with a meaningful Pearson correlation coefficient of 0.124. Conclusions: Higher BMI was associated with lower PSA levels and higher IPSS and QoL scores. Meanwhile, PV increased with BMI. Although obese individuals had a greater PV, obesity did not aggravate lower urinary tract symptoms.