Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents
Abstract Between 2009 and 2013, a large cross-sectional study on the health consequences of the Chernobyl nuclear accident was performed in the contaminated and uncontaminated territories of the Bryansk Oblast (Russian Federation). The objective of this work was to confirm or refute a possible assoc...
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doaj-71712e424848443cb4e4b653e6bdb56c2021-02-07T12:33:18ZengNature Publishing GroupScientific Reports2045-23222021-02-011111910.1038/s41598-021-82314-0Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescentsGeraldine Landon0Isabelle Denjoy1Enora Clero2Aleksandr Silenok3Irina Kurnosova4Andrey Butsenin5Patrick Gourmelon6Jean-Rene Jourdain7Division of Health, Institute for Radiological Protection and Nuclear Safety (IRSN)Department of Cardiology, Bichat Hospital (AP-HP)Division of Health, Institute for Radiological Protection and Nuclear Safety (IRSN)Department of Cardiology, Bryansk Diagnostic CenterDepartment of Cardiology, Bryansk Diagnostic CenterDepartment of Cardiology, Bryansk Diagnostic CenterDivision of Health, Institute for Radiological Protection and Nuclear Safety (IRSN)European and International Affairs Department, Institute for Radiological Protection and Nuclear Safety (IRSN)Abstract Between 2009 and 2013, a large cross-sectional study on the health consequences of the Chernobyl nuclear accident was performed in the contaminated and uncontaminated territories of the Bryansk Oblast (Russian Federation). The objective of this work was to confirm or refute a possible association between childhood cardiac arrhythmia and a chronic exposure to caesium-137. As part of this study, a large number of electrocardiographic and cardiac ultrasound parameters were collected from 18,152 children aged 2–18 years including 12,512 healthy ones not contaminated with caesium-137. It seemed therefore relevant for us to share in a second publication these medical data based on healthy and uncontaminated children with the scientific community because of the large quantities and the limited availability of such kind of data. In the present study, relating to electrocardiographic parameters, the measurements performed fully reflect the expected evolution of the paediatric electrocardiogram between 5 and 18 years of age. Thus, the median values were generally quite close to those available in the literature. In contrast, differences in the 2nd and 98th percentiles were notable and could be explained in particular by the type of equipment used, the number of subjects included in the study and racial disparities. As for echocardiographic parameters, the evolution of the measured values in age groups is consistent with what was expected considering factors such as growth. In comparison with other scientific studies that have investigated these echocardiographic parameters, some differences by age groups have been identified. The ethnic factor truly appears to be a relevant feature to consider. In view of the results, it appeared essential to the authors to approach the methodological conditions of the scientific studies already published on the topic to be truly comparable and thus to provide a reliable answer on a topic for which real expectations in terms of medical care are required.https://doi.org/10.1038/s41598-021-82314-0 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Geraldine Landon Isabelle Denjoy Enora Clero Aleksandr Silenok Irina Kurnosova Andrey Butsenin Patrick Gourmelon Jean-Rene Jourdain |
spellingShingle |
Geraldine Landon Isabelle Denjoy Enora Clero Aleksandr Silenok Irina Kurnosova Andrey Butsenin Patrick Gourmelon Jean-Rene Jourdain Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents Scientific Reports |
author_facet |
Geraldine Landon Isabelle Denjoy Enora Clero Aleksandr Silenok Irina Kurnosova Andrey Butsenin Patrick Gourmelon Jean-Rene Jourdain |
author_sort |
Geraldine Landon |
title |
Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents |
title_short |
Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents |
title_full |
Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents |
title_fullStr |
Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents |
title_full_unstemmed |
Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents |
title_sort |
reference values of electrographic and cardiac ultrasound parameters in russian healthy children and adolescents |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-02-01 |
description |
Abstract Between 2009 and 2013, a large cross-sectional study on the health consequences of the Chernobyl nuclear accident was performed in the contaminated and uncontaminated territories of the Bryansk Oblast (Russian Federation). The objective of this work was to confirm or refute a possible association between childhood cardiac arrhythmia and a chronic exposure to caesium-137. As part of this study, a large number of electrocardiographic and cardiac ultrasound parameters were collected from 18,152 children aged 2–18 years including 12,512 healthy ones not contaminated with caesium-137. It seemed therefore relevant for us to share in a second publication these medical data based on healthy and uncontaminated children with the scientific community because of the large quantities and the limited availability of such kind of data. In the present study, relating to electrocardiographic parameters, the measurements performed fully reflect the expected evolution of the paediatric electrocardiogram between 5 and 18 years of age. Thus, the median values were generally quite close to those available in the literature. In contrast, differences in the 2nd and 98th percentiles were notable and could be explained in particular by the type of equipment used, the number of subjects included in the study and racial disparities. As for echocardiographic parameters, the evolution of the measured values in age groups is consistent with what was expected considering factors such as growth. In comparison with other scientific studies that have investigated these echocardiographic parameters, some differences by age groups have been identified. The ethnic factor truly appears to be a relevant feature to consider. In view of the results, it appeared essential to the authors to approach the methodological conditions of the scientific studies already published on the topic to be truly comparable and thus to provide a reliable answer on a topic for which real expectations in terms of medical care are required. |
url |
https://doi.org/10.1038/s41598-021-82314-0 |
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