The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

In adult mammals, hematopoiesis, the production of blood cells from hematopoietic stem and progenitor cells (HSPCs), is tightly regulated by extrinsic signals from the microenvironment called ‘niche’. Bone marrow HSPCs are heterogeneous and controlled by both endosteal and vascular niches. The Droso...

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Bibliographic Details
Main Authors: Manon Destalminil-Letourneau, Ismaël Morin-Poulard, Yushun Tian, Nathalie Vanzo, Michele Crozatier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
hematopoiesis
microenvironment/niche
lymph gland
cardiac/vascular cells
Drosophila
FGF signaling
Online Access:https://elifesciences.org/articles/64672

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