Generation of a protective murine monoclonal antibody against the stem of influenza hemagglutinins from group 1 viruses and identification of resistance mutations against it.
Vaccines that elicit broadly cross-neutralizing antibodies, including antibodies that target the conserved stem of hemagglutinin (HA), are being developed as a strategy for next-generation influenza vaccines that protect against influenza across multiple years. However, efficient induction of cross-...
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Bibliographic Details
Main Authors: |
Wei Wang,
Russell Vassell,
Hyo Sook Song,
Qiong Chen,
Paul W Keller,
Swati Verma,
Esmeralda Alvarado-Facundo,
Hongquan Wan,
Falko Schmeisser,
Clement A Meseda,
Jerry P Weir,
Carol D Weiss |
Format: | Article
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Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE
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Online Access: | https://doi.org/10.1371/journal.pone.0222436
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