Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB

Summary: Legionella pneumophila is an intracellular pathogen that requires nutrients from the host for its replication. It has been shown that replicating L. pneumophila prefers amino acids as main sources of carbon and energy. The homeostasis of amino acids in eukaryotic cells is regulated by the t...

Full description

Bibliographic Details
Main Authors: Wendy H.J. Beck, Dongsung Kim, Jishnu Das, Haiyuan Yu, Marcus B. Smolka, Yuxin Mao
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304879