An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A
There are rare instances where patients with acute hepatitis A virus infection subsequently developed autoimmune hepatitis. The diagnosis of autoimmune hepatitis in this setting is challenging. Furthermore, information on treatment with steroids or other immune suppressants, duration of therapy and...
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2020-11-01
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doaj-7183f1a6c84848d9b54bd37859fd92432021-06-09T05:57:13ZengElsevierAnnals of Hepatology1665-26812020-11-01196694696An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis AVijay S.-Are0Lindsay Yoder1Niharika Samala2Lauren Nephew3Craig Lammert4Raj Vuppalanchi5Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USADivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USADivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USADivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USADivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USACorresponding author at: Associate Professor of Medicine,Division of Gastroenterology and Hepatology, Indiana University School of Medicine.702 Rotary Circle, Suite 225 Indianapolis, IN 46202, USA; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis IN, USAThere are rare instances where patients with acute hepatitis A virus infection subsequently developed autoimmune hepatitis. The diagnosis of autoimmune hepatitis in this setting is challenging. Furthermore, information on treatment with steroids or other immune suppressants, duration of therapy and possibility of treatment discontinuation is currently unclear. Here we report a case series of four patients with histology proven autoimmune hepatitis after hepatitis A virus infection. We describe the presenting features, diagnosis, treatment and long-term outcomes of these cases. This case series provides a insight into the clinical presentation and treatment of autoimmune hepatitis after hepatitis A infection with interesting take home points for clinical hepatologists.http://www.sciencedirect.com/science/article/pii/S1665268120301678autoimmunehepatitis A virusinterface hepatitis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Vijay S.-Are Lindsay Yoder Niharika Samala Lauren Nephew Craig Lammert Raj Vuppalanchi |
spellingShingle |
Vijay S.-Are Lindsay Yoder Niharika Samala Lauren Nephew Craig Lammert Raj Vuppalanchi An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A Annals of Hepatology autoimmune hepatitis A virus interface hepatitis |
author_facet |
Vijay S.-Are Lindsay Yoder Niharika Samala Lauren Nephew Craig Lammert Raj Vuppalanchi |
author_sort |
Vijay S.-Are |
title |
An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A |
title_short |
An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A |
title_full |
An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A |
title_fullStr |
An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A |
title_full_unstemmed |
An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A |
title_sort |
outbreak presents an opportunity to learn about a rare phenotype: autoimmune hepatitis after acute hepatitis a |
publisher |
Elsevier |
series |
Annals of Hepatology |
issn |
1665-2681 |
publishDate |
2020-11-01 |
description |
There are rare instances where patients with acute hepatitis A virus infection subsequently developed autoimmune hepatitis. The diagnosis of autoimmune hepatitis in this setting is challenging. Furthermore, information on treatment with steroids or other immune suppressants, duration of therapy and possibility of treatment discontinuation is currently unclear. Here we report a case series of four patients with histology proven autoimmune hepatitis after hepatitis A virus infection. We describe the presenting features, diagnosis, treatment and long-term outcomes of these cases. This case series provides a insight into the clinical presentation and treatment of autoimmune hepatitis after hepatitis A infection with interesting take home points for clinical hepatologists. |
topic |
autoimmune hepatitis A virus interface hepatitis |
url |
http://www.sciencedirect.com/science/article/pii/S1665268120301678 |
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