The Chloride Anion Acts as a Second Messenger in Mammalian Cells - Modifying the Expression of Specific Genes
Background/Aims: Cystic Fibrosis (CF) is caused by mutations in the CFTR gene, encoding a cAMP-activated chloride (Cl-) channel. We have previously demonstrated that the expression of several genes can be modulated by the CFTR activity; among them, SRC, MTND4, CISD1, and IL1B. However, the CFTR sign...
Main Authors: | Ángel G. Valdivieso, Mariángeles Clauzure, Macarena Massip-Copiz, Tomás A. Santa-Coloma |
---|---|
Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2016-01-01
|
Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/438608 |
Similar Items
-
Twenty years of fluorescence imaging of intracellular Chloride.
by: Daniele eArosio, et al.
Published: (2014-08-01) -
Implication de BMP6, GLRX5 et la H+/K+ ATPase dans les troubles du métabolisme de fer : de la physiologie à la pathologie
by: Daher, Raed
Published: (2017) -
The Alteration of Chloride Homeostasis/GABAergic Signaling in Brain Disorders: Could Oxidative Stress Play a Role?
by: Provvidenza M. Abruzzo, et al.
Published: (2021-08-01) -
KCC2-dependent Steady-state Intracellular Chloride Concentration and pH in Cortical Layer 2/3 Neurons of Anesthetized and Awake Mice
by: Juan C. Boffi, et al.
Published: (2018-01-01) -
Reactions of Thionyl Chloride, Sulfuryl Chloride, and Chlorosulphonic Acid with Various Types of Hydrocarbons
by: Shepherd, George
Published: (1940)