Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal
About 400 million individuals worldwide have been affected by the inherited disorder of glucose-6-phosphate dehydrogenase (G6PD) deficiency that predisposes individuals to neonatal jaundice or hemolytic crisis due to drugs or infections. A descriptive observational study with longitudinal design was...
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Wolters Kluwer Medknow Publications
2012-01-01
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doaj-719875d161d74fb4907940d940f28b8a2020-11-24T23:18:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2012-01-0156214614810.4103/0019-557X.99908Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West BengalSukamal BisoiSumanta ChakrabortyDipankar ChattopadhyayBiswajit BiswasSarbajit RayAbout 400 million individuals worldwide have been affected by the inherited disorder of glucose-6-phosphate dehydrogenase (G6PD) deficiency that predisposes individuals to neonatal jaundice or hemolytic crisis due to drugs or infections. A descriptive observational study with longitudinal design was undertaken among 109 live newborns, delivered in labor room of IPGME and R, Kolkata during the period from June to August 2009. An objective of the study was to estimate the occurrence of G6PD deficiency among newborns and its association with different socio-demographic, clinical and gestational characteristics. 14.68% newborns were found G6PD deficient. This occurrence was not significantly related to gender, religion and ethnicity, consanguineous marriage of the parents, gestational age and birth weight of the baby. Development of severe jaundice (total serum bilirubin >15 mg/dl) was found 23.8% among G6PD deficient babies and 12.5% among non-G6PD deficient. This difference was statistically not significant.http://www.ijph.in/article.asp?issn=0019-557X;year=2012;volume=56;issue=2;spage=146;epage=148;aulast=BisoiGlucose-6-phosphate dehydrogenase deficiencyGestational ageHemolytic crisisSemi-quantitative assay |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sukamal Bisoi Sumanta Chakraborty Dipankar Chattopadhyay Biswajit Biswas Sarbajit Ray |
spellingShingle |
Sukamal Bisoi Sumanta Chakraborty Dipankar Chattopadhyay Biswajit Biswas Sarbajit Ray Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal Indian Journal of Public Health Glucose-6-phosphate dehydrogenase deficiency Gestational age Hemolytic crisis Semi-quantitative assay |
author_facet |
Sukamal Bisoi Sumanta Chakraborty Dipankar Chattopadhyay Biswajit Biswas Sarbajit Ray |
author_sort |
Sukamal Bisoi |
title |
Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal |
title_short |
Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal |
title_full |
Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal |
title_fullStr |
Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal |
title_full_unstemmed |
Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal |
title_sort |
glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in west bengal |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Public Health |
issn |
0019-557X |
publishDate |
2012-01-01 |
description |
About 400 million individuals worldwide have been affected by the inherited disorder of glucose-6-phosphate dehydrogenase (G6PD) deficiency that predisposes individuals to neonatal jaundice or hemolytic crisis due to drugs or infections. A descriptive observational study with longitudinal design was undertaken among 109 live newborns, delivered in labor room of IPGME and R, Kolkata during the period from June to August 2009. An objective of the study was to estimate the occurrence of G6PD deficiency among newborns and its association with different socio-demographic, clinical and gestational characteristics. 14.68% newborns were found G6PD deficient. This occurrence was not significantly related to gender, religion and ethnicity, consanguineous marriage of the parents, gestational age and birth weight of the baby. Development of severe jaundice (total serum bilirubin >15 mg/dl) was found 23.8% among G6PD deficient babies and 12.5% among non-G6PD deficient. This difference was statistically not significant. |
topic |
Glucose-6-phosphate dehydrogenase deficiency Gestational age Hemolytic crisis Semi-quantitative assay |
url |
http://www.ijph.in/article.asp?issn=0019-557X;year=2012;volume=56;issue=2;spage=146;epage=148;aulast=Bisoi |
work_keys_str_mv |
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