Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice

Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice

Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) is commonly associated with obesity and characterized by excessive lipid accumulation and liver inflammation. The T cell immunoglobulin and mucin domain 1 (Tim-1), also known as hepatitis A virus cellular receptor 1 (Havc...

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Bibliographic Details
Main Authors: Jasmine George, Yuanyuan Zhang, Jacob Sloan, Joya M. Sims, John D. Imig, Xueying Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
non-alcoholic steatohepatitis
high-fat diet
lipid metabolism
inflammation
Tim-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.747794/full

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