Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence
Asthma is the commonest chronic disease affecting airways in humans and has an increasing global disease burden. Inhaled corticosteroids (ICS) are the first-line therapeutic option for asthma, and addition of a long-acting beta 2-agonist (LABA) has been shown to improve asthma control. A combination...
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doaj-71ef90596851448c97b113864d44e3562021-07-02T13:03:41ZengHindawi LimitedCanadian Respiratory Journal1198-22411916-72452020-01-01202010.1155/2020/86313168631316Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve AdherenceV. Rajesh0Jolsana Augustine1R. Divya2Melcy Cleetus3Department of Pulmonary Medicine, Rajagiri Hospital, Chunangamvely, Aluva, Kochi, Kerala, IndiaDepartment of Pulmonary Medicine, Rajagiri Hospital, Chunangamvely, Aluva, Kochi, Kerala, IndiaDepartment of Pulmonary Medicine, Rajagiri Hospital, Chunangamvely, Aluva, Kochi, Kerala, IndiaDepartment of Pulmonary Medicine, Rajagiri Hospital, Chunangamvely, Aluva, Kochi, Kerala, IndiaAsthma is the commonest chronic disease affecting airways in humans and has an increasing global disease burden. Inhaled corticosteroids (ICS) are the first-line therapeutic option for asthma, and addition of a long-acting beta 2-agonist (LABA) has been shown to improve asthma control. A combination of the two agents in a single inhaler is beneficial with regard to ease of administration and patient compliance. Various ICS-LABA formulations are available across various countries in the world, one among them being formoterol-fluticasone. Both formoterol and fluticasone have pharmacologic peculiarities which places the combination in a uniquely advantageous position when it comes to asthma therapy. The present review focuses on some of the, hitherto, less explored aspects of this combination inhaler such as real-world efficacy, impact on budget allocation, results of switch-over therapy, and potential to improve adherence to asthma treatment. It also provides practical recommendations on positioning it in real-world asthma management.http://dx.doi.org/10.1155/2020/8631316 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
V. Rajesh Jolsana Augustine R. Divya Melcy Cleetus |
spellingShingle |
V. Rajesh Jolsana Augustine R. Divya Melcy Cleetus Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence Canadian Respiratory Journal |
author_facet |
V. Rajesh Jolsana Augustine R. Divya Melcy Cleetus |
author_sort |
V. Rajesh |
title |
Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence |
title_short |
Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence |
title_full |
Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence |
title_fullStr |
Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence |
title_full_unstemmed |
Inhaled Formoterol-Fluticasone Single Inhaler Therapy in Asthma: Real-World Efficacy, Budget Impact, and Potential to Improve Adherence |
title_sort |
inhaled formoterol-fluticasone single inhaler therapy in asthma: real-world efficacy, budget impact, and potential to improve adherence |
publisher |
Hindawi Limited |
series |
Canadian Respiratory Journal |
issn |
1198-2241 1916-7245 |
publishDate |
2020-01-01 |
description |
Asthma is the commonest chronic disease affecting airways in humans and has an increasing global disease burden. Inhaled corticosteroids (ICS) are the first-line therapeutic option for asthma, and addition of a long-acting beta 2-agonist (LABA) has been shown to improve asthma control. A combination of the two agents in a single inhaler is beneficial with regard to ease of administration and patient compliance. Various ICS-LABA formulations are available across various countries in the world, one among them being formoterol-fluticasone. Both formoterol and fluticasone have pharmacologic peculiarities which places the combination in a uniquely advantageous position when it comes to asthma therapy. The present review focuses on some of the, hitherto, less explored aspects of this combination inhaler such as real-world efficacy, impact on budget allocation, results of switch-over therapy, and potential to improve adherence to asthma treatment. It also provides practical recommendations on positioning it in real-world asthma management. |
url |
http://dx.doi.org/10.1155/2020/8631316 |
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