Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor

Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor

Despite the pivotal role of natural killer (NK) cells in defenses against tumors, their exploitation in cancer treatment is still limited due to their reduced ability to reaching tumor sites and the inhibitory effects of tumor microenvironment (TME) on their function. In this study, we have characte...

Full description

Bibliographic Details
Main Authors: Anna Laura Di Pace, Nicola Tumino, Francesca Besi, Claudia Alicata, Libenzio Adrian Conti, Enrico Munari, Enrico Maggi, Paola Vacca, Lorenzo Moretta
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
exosomes
nk cells
dnam1
cytotoxicity
cancer
tumor therapy
Online Access:https://www.mdpi.com/2072-6694/12/3/661

Similar Items

Similar Items