Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats[S]

Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats[S]

High-calorie food leads to nonalcoholic fatty liver disease (NAFLD) through dysregulation of genes involved in lipid metabolism, but the precise mechanism remains unclear. DNA methylation represents one of the mechanisms that contributes to dysregulation of gene expression via interaction with envir...

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Bibliographic Details
Main Authors: XinXia Chang, HongMei Yan, Jing Fei, MingHong Jiang, HongGuang Zhu, DaRu Lu, Xin Gao
Format: Article
Language:English
Published: Elsevier 2010-09-01
Series:Journal of Lipid Research
Subjects:
DNA methylation
microsomal triglyceride transfer protein
nonalcoholic fatty liver disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520422825

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