Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study
Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical...
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Language: | English |
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MDPI AG
2020-11-01
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Series: | International Journal of Environmental Research and Public Health |
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Online Access: | https://www.mdpi.com/1660-4601/17/22/8411 |
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Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jéssica Alonso-Molero Trinidad Dierssen-Sotos Ines Gomez-Acebo Nerea Fernandez de Larrea Baz Marcela Guevara Pilar Amiano Gemma Castaño-Vinyals Tania Fernandez-Villa Victor Moreno Juan Bayo Ana Molina-Barceloa María Fernández-Ortíz Claudia Suarez-Calleja Rafael Marcos-Gragera Xavier Castells Leire Gil-Majuelo Eva Ardanaz Beatriz Pérez-Gómez Manolis Kogevinas Marina Pollán Javier Llorca |
spellingShingle |
Jéssica Alonso-Molero Trinidad Dierssen-Sotos Ines Gomez-Acebo Nerea Fernandez de Larrea Baz Marcela Guevara Pilar Amiano Gemma Castaño-Vinyals Tania Fernandez-Villa Victor Moreno Juan Bayo Ana Molina-Barceloa María Fernández-Ortíz Claudia Suarez-Calleja Rafael Marcos-Gragera Xavier Castells Leire Gil-Majuelo Eva Ardanaz Beatriz Pérez-Gómez Manolis Kogevinas Marina Pollán Javier Llorca Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study International Journal of Environmental Research and Public Health quality of life breast cancer SF-12 FBSI educational level |
author_facet |
Jéssica Alonso-Molero Trinidad Dierssen-Sotos Ines Gomez-Acebo Nerea Fernandez de Larrea Baz Marcela Guevara Pilar Amiano Gemma Castaño-Vinyals Tania Fernandez-Villa Victor Moreno Juan Bayo Ana Molina-Barceloa María Fernández-Ortíz Claudia Suarez-Calleja Rafael Marcos-Gragera Xavier Castells Leire Gil-Majuelo Eva Ardanaz Beatriz Pérez-Gómez Manolis Kogevinas Marina Pollán Javier Llorca |
author_sort |
Jéssica Alonso-Molero |
title |
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study |
title_short |
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study |
title_full |
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study |
title_fullStr |
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study |
title_full_unstemmed |
Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study |
title_sort |
quality of life in a cohort of 1078 women diagnosed with breast cancer in spain: 7-year follow-up results in the mcc-spain study |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1661-7827 1660-4601 |
publishDate |
2020-11-01 |
description |
Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017–2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run. |
topic |
quality of life breast cancer SF-12 FBSI educational level |
url |
https://www.mdpi.com/1660-4601/17/22/8411 |
work_keys_str_mv |
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doaj-7215a9dec6e3451db8ecf3785068a69a2020-11-25T04:07:00ZengMDPI AGInternational Journal of Environmental Research and Public Health1661-78271660-46012020-11-01178411841110.3390/ijerph17228411Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain StudyJéssica Alonso-Molero0Trinidad Dierssen-Sotos1Ines Gomez-Acebo2Nerea Fernandez de Larrea Baz3Marcela Guevara4Pilar Amiano5Gemma Castaño-Vinyals6Tania Fernandez-Villa7Victor Moreno8Juan Bayo9Ana Molina-Barceloa10María Fernández-Ortíz11Claudia Suarez-Calleja12Rafael Marcos-Gragera13Xavier Castells14Leire Gil-Majuelo15Eva Ardanaz16Beatriz Pérez-Gómez17Manolis Kogevinas18Marina Pollán19Javier Llorca20Department of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, SpainDepartment of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, SpainDepartment of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainGrupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS), Instituto de Biomedicina (IBIOMED), Universidad de León, 24071 León, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainServicio de Oncología del Hospital Universitario Juan Ramón Jiménez, 21005 Huelva, SpainCancer and Public Health Area, FISABIO—Public Health, 46035 Valencia, SpainDepartment of Preventive Medicine and Public Health, University of Cantabria—IDIVAL, 39011 Santander, SpainÁrea de Medicina Preventiva, Departamento de Medicina, Universidad de Oviedo, 33006 Asturias, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainEpidemiology and Evaluation Department, IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, SpainPublic Health Division of Gipuzkoa, Biodonostia Research Institute, 20014 San Sebastian, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainCIBER Epidemiologia y Salud Pública (CIBERESP), 28029 Madrid, SpainBreast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017–2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run.https://www.mdpi.com/1660-4601/17/22/8411quality of lifebreast cancerSF-12FBSIeducational level |