Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals
Egia-Mendikute et al. develop a multiplexed flow cytometric bead array to simultaneously detect antibodies reactive to three immunogenic SARS-CoV-2 proteins. More sensitive than ELISA, they detected N-reactive antibodies in COVID-19-negative individuals with this assay, showing it to have superior p...
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Bibliographic Details
Main Authors: |
Leire Egia-Mendikute,
Alexandre Bosch,
Endika Prieto-Fernández,
So Young Lee,
Borja Jiménez-Lasheras,
Ana García del Río,
Asier Antoñana-Vildosola,
Chiara Bruzzone,
Maider Bizkarguenaga,
Nieves Embade,
Rubén Gil-Redondo,
María Luz Martínez-Chantar,
Marcos López-Hoyos,
Nicola G. A. Abrescia,
José M. Mato,
Óscar Millet,
Asís Palazón |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2021-04-01
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Series: | Communications Biology
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Online Access: | https://doi.org/10.1038/s42003-021-02011-6
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