Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study
Hongna Dong,1,* Yuqiu Hao,1,* Dapeng Li,2 Zhenzhong Su,1 Wei Li,1 Bingqing Shi,1 Peng Gao1 1Department of Respiratory Medicine, Second Hospital of Jilin University, Changchun, Jilin Province, People’s Republic of China; 2Department of Respiratory Medicine, Affiliated Hospital of Jilin Medi...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Dove Medical Press
2020-09-01
|
Series: | International Journal of COPD |
Subjects: | |
Online Access: | https://www.dovepress.com/risk-factors-for-acute-exacerbation-of-chronic-obstructive-pulmonary-d-peer-reviewed-article-COPD |
id |
doaj-721dfd15711d44a69838d9a12bd81552 |
---|---|
record_format |
Article |
spelling |
doaj-721dfd15711d44a69838d9a12bd815522020-11-25T01:38:36ZengDove Medical PressInternational Journal of COPD1178-20052020-09-01Volume 152249225657359Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional StudyDong HHao YLi DSu ZLi WShi BGao PHongna Dong,1,* Yuqiu Hao,1,* Dapeng Li,2 Zhenzhong Su,1 Wei Li,1 Bingqing Shi,1 Peng Gao1 1Department of Respiratory Medicine, Second Hospital of Jilin University, Changchun, Jilin Province, People’s Republic of China; 2Department of Respiratory Medicine, Affiliated Hospital of Jilin Medical College, Jilin, Jilin Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Peng GaoDepartment of Respiratory, Second Hospital of Jilin University, Changchun, Jilin Province, People’s Republic of ChinaTel/Fax +86-43181136866Email gaopeng1234@sina.comBackground: The exacerbation of chronic obstructive pulmonary disease (COPD) seriously affects the patient’s quality of life and prognosis. This multicenter cross-sectional study investigated the characteristics of stable COPD and risk factors for acute exacerbation of COPD (AECOPD) in patients in Changchun, Jilin Province, China.Methods: The study included 400 outpatients admitted to four secondary hospitals and four tertiary hospitals in Jilin Province from March 2018 to March 2019. Data on the general condition of stable COPD patients, patient self-management, COPD Assessment Test (CAT) scores, number of acute exacerbations in the past 12 months, and medications received during the study period were collected using a questionnaire.Results: Sociodemographic characteristics and clinical data were obtained from 306 patients, and drug prescription data were obtained from 329 patients. Pearson correlation analysis revealed that CAT scores were positively correlated with the number of acute exacerbations. Age, education level, smoking history, disease duration, number of comorbidities, and the presence of ischemic heart disease (IHD) were associated with AECOPD. Moreover, the level of education, disease duration, and the presence of IHD were independent risk factors for AECOPD. Poor compliance due to the lack of understanding of the disease and the high cost of treatment is a risk factor for AECOPD. In addition, increased air pollution in industrial cities and vitamin D deficiency are closely related to AECOPD.Conclusion: Low education level, long disease duration, and the presence of IHD may promote the exacerbation and poor control of COPD in patients in Jilin Province.Keywords: COPD, exacerbation, risk factors, Jilin Provincehttps://www.dovepress.com/risk-factors-for-acute-exacerbation-of-chronic-obstructive-pulmonary-d-peer-reviewed-article-COPDcopdexacerbationrisk factorsjilin province |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dong H Hao Y Li D Su Z Li W Shi B Gao P |
spellingShingle |
Dong H Hao Y Li D Su Z Li W Shi B Gao P Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study International Journal of COPD copd exacerbation risk factors jilin province |
author_facet |
Dong H Hao Y Li D Su Z Li W Shi B Gao P |
author_sort |
Dong H |
title |
Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study |
title_short |
Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study |
title_full |
Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study |
title_fullStr |
Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study |
title_full_unstemmed |
Risk Factors for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Industrial Regions of China: A Multicenter Cross-Sectional Study |
title_sort |
risk factors for acute exacerbation of chronic obstructive pulmonary disease in industrial regions of china: a multicenter cross-sectional study |
publisher |
Dove Medical Press |
series |
International Journal of COPD |
issn |
1178-2005 |
publishDate |
2020-09-01 |
description |
Hongna Dong,1,* Yuqiu Hao,1,* Dapeng Li,2 Zhenzhong Su,1 Wei Li,1 Bingqing Shi,1 Peng Gao1 1Department of Respiratory Medicine, Second Hospital of Jilin University, Changchun, Jilin Province, People’s Republic of China; 2Department of Respiratory Medicine, Affiliated Hospital of Jilin Medical College, Jilin, Jilin Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Peng GaoDepartment of Respiratory, Second Hospital of Jilin University, Changchun, Jilin Province, People’s Republic of ChinaTel/Fax +86-43181136866Email gaopeng1234@sina.comBackground: The exacerbation of chronic obstructive pulmonary disease (COPD) seriously affects the patient’s quality of life and prognosis. This multicenter cross-sectional study investigated the characteristics of stable COPD and risk factors for acute exacerbation of COPD (AECOPD) in patients in Changchun, Jilin Province, China.Methods: The study included 400 outpatients admitted to four secondary hospitals and four tertiary hospitals in Jilin Province from March 2018 to March 2019. Data on the general condition of stable COPD patients, patient self-management, COPD Assessment Test (CAT) scores, number of acute exacerbations in the past 12 months, and medications received during the study period were collected using a questionnaire.Results: Sociodemographic characteristics and clinical data were obtained from 306 patients, and drug prescription data were obtained from 329 patients. Pearson correlation analysis revealed that CAT scores were positively correlated with the number of acute exacerbations. Age, education level, smoking history, disease duration, number of comorbidities, and the presence of ischemic heart disease (IHD) were associated with AECOPD. Moreover, the level of education, disease duration, and the presence of IHD were independent risk factors for AECOPD. Poor compliance due to the lack of understanding of the disease and the high cost of treatment is a risk factor for AECOPD. In addition, increased air pollution in industrial cities and vitamin D deficiency are closely related to AECOPD.Conclusion: Low education level, long disease duration, and the presence of IHD may promote the exacerbation and poor control of COPD in patients in Jilin Province.Keywords: COPD, exacerbation, risk factors, Jilin Province |
topic |
copd exacerbation risk factors jilin province |
url |
https://www.dovepress.com/risk-factors-for-acute-exacerbation-of-chronic-obstructive-pulmonary-d-peer-reviewed-article-COPD |
work_keys_str_mv |
AT dongh riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT haoy riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT lid riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT suz riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT liw riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT shib riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy AT gaop riskfactorsforacuteexacerbationofchronicobstructivepulmonarydiseaseinindustrialregionsofchinaamulticentercrosssectionalstudy |
_version_ |
1725052896015286272 |