Protective effects of a composition of Chinese herbs-Gurigumu-13 on retinal ganglion cell apoptosis in DBA/2J glaucoma mouse model

Protective effects of a composition of Chinese herbs-Gurigumu-13 on retinal ganglion cell apoptosis in DBA/2J glaucoma mouse model

AIM: To explore the concrete mechanism of a Mongolian compound medicine-Gurigumu-13 (GRGM) for glaucoma treatment. METHODS: DBA/2J mice, as glaucoma models, were intragastric administrated with GRGM to study the effect of GRGM on retinal ganglion cells (RGCs). The loss of RGCs was evaluated with th...

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Bibliographic Details
Main Authors: Qiu-Li Zhang, Wei Wang, Yan Jiang, Tian-Zi Zhang, Zhan-Jun Lu, Ao Jiang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-03-01
Series:International Journal of Ophthalmology
Subjects:
368
glaucoma
retinal ganglion cells
oxidative stress
endoplasmic reticulum stress
Online Access:http://www.ijo.cn/en_publish/2018/3/20180303.pdf

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