Adiponectin-Based Peptide (ADP355) Inhibits Transforming Growth Factor-β1-Induced Fibrosis in Keloids

Adiponectin-Based Peptide (ADP355) Inhibits Transforming Growth Factor-β1-Induced Fibrosis in Keloids

Keloids, benign cutaneous overgrowths of dermal fibroblasts, are caused by pathologic scarring of wounds during healing. Current surgical and therapeutic modalities are unsatisfactory. Although adiponectin has shown an antifibrotic effect, its large size and insolubility limit its potential use in k...

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Bibliographic Details
Main Authors: Claudia C. Darmawan, Sara E. Montenegro, Gwanghyun Jo, Novi Kusumaningrum, Si-Hyung Lee, Jin-Ho Chung, Je-Ho Mun
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
keloid
adiponectin
peptide
treatment
fibrosis
scarring
Online Access:https://www.mdpi.com/1422-0067/21/8/2833

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