Regulation of Renal Fibrosis by Macrophage Polarization

Regulation of Renal Fibrosis by Macrophage Polarization

Background/Aims: Since renal fibrosis always predisposes end-stage renal disease, elucidation of the molecular mechanisms that underlie the progression of renal fibrosis may substantially improve the understanding and treatment for renal failure. Previous studies have highlighted an important counte...

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Bibliographic Details
Main Authors: Bixia Pan, Guohui Liu, Zongpei Jiang, Dongwen Zheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Transforming growth factor β 1 (TGFβ1)
E-cadherin
Macrophages
Unilateral ureteral obstruction (UUO)
Bone morphogenic protein 7 (BMP7)
Renal fibrosis
Epithelial-to-mesenchymal transition (EMT)
α-smooth muscle actin (α-SMA)
Online Access:http://www.karger.com/Article/FullText/373932

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http://www.karger.com/Article/FullText/373932

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