Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice

Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice

BSB mice exhibit a wide range of obesity despite being produced by a backcross of lean C57BL/6J (B) × lean Mus spretus (SPRET/Pt) F1 animals × B. Previous linkage studies identified a quantitative trait locus (QTL) on mouse chromosome 7 with coincident peaks for hepatic lipase activity, obesity, and...

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Bibliographic Details
Main Authors: Nengjun Yi, Sally Chiu, David B. Allison, Janis S. Fisler, Craig H. Warden
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Journal of Lipid Research
Subjects:
gene × gene
mouse
obesity
hepatic lipase
Bayesian
quantitative trait locus
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341353

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http://www.sciencedirect.com/science/article/pii/S0022227520341353

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