TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage

Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.

Bibliographic Details
Main Authors:	Nam Soo Lee, Hee Jin Chung, Hyoung-June Kim, Seo Yun Lee, Jae-Hoon Ji, Yoojeong Seo, Seung Hun Han, Minji Choi, Miyong Yun, Seok-Geun Lee, Kyungjae Myung, Yonghwan Kim, Ho Chul Kang, Hongtae Kim
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-01-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms10463

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spelling	doaj-72bf4c78c1ad40a48afe36239425d37a2021-05-11T10:47:40ZengNature Publishing GroupNature Communications2041-17232016-01-017111310.1038/ncomms10463TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damageNam Soo Lee0Hee Jin Chung1Hyoung-June Kim2Seo Yun Lee3Jae-Hoon Ji4Yoojeong Seo5Seung Hun Han6Minji Choi7Miyong Yun8Seok-Geun Lee9Kyungjae Myung10Yonghwan Kim11Ho Chul Kang12Hongtae Kim13Department of Biological Sciences, Sungkyunkwan UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityGenomic Instability Research Center, Ajou University School of MedicineGenomic Instability Research Center, Ajou University School of MedicineDepartment of Biological Sciences, Sookmyung Women's UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityCenter for Genomic Integrity, Institute for Basic Science (IBS), Ulsan National Institute of Science and TechnologyDepartment of Biological Sciences, Sookmyung Women's UniversityGenomic Instability Research Center, Ajou University School of MedicineDepartment of Biological Sciences, Sungkyunkwan UniversityRecruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.https://doi.org/10.1038/ncomms10463
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim
spellingShingle	Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage Nature Communications
author_facet	Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim
author_sort	Nam Soo Lee
title	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_short	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_full	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_fullStr	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_full_unstemmed	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
title_sort	traip/rnf206 is required for recruitment of rap80 to sites of dna damage
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-01-01
description	Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.
url	https://doi.org/10.1038/ncomms10463
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TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage

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