TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.
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2016-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10463 |
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doaj-72bf4c78c1ad40a48afe36239425d37a2021-05-11T10:47:40ZengNature Publishing GroupNature Communications2041-17232016-01-017111310.1038/ncomms10463TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damageNam Soo Lee0Hee Jin Chung1Hyoung-June Kim2Seo Yun Lee3Jae-Hoon Ji4Yoojeong Seo5Seung Hun Han6Minji Choi7Miyong Yun8Seok-Geun Lee9Kyungjae Myung10Yonghwan Kim11Ho Chul Kang12Hongtae Kim13Department of Biological Sciences, Sungkyunkwan UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityGenomic Instability Research Center, Ajou University School of MedicineGenomic Instability Research Center, Ajou University School of MedicineDepartment of Biological Sciences, Sookmyung Women's UniversityDepartment of Biological Sciences, Sungkyunkwan UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityDepartment of Science in Korean Medicine, College of Korean Medicine, Kyung Hee UniversityCenter for Genomic Integrity, Institute for Basic Science (IBS), Ulsan National Institute of Science and TechnologyDepartment of Biological Sciences, Sookmyung Women's UniversityGenomic Instability Research Center, Ajou University School of MedicineDepartment of Biological Sciences, Sungkyunkwan UniversityRecruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.https://doi.org/10.1038/ncomms10463 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim |
spellingShingle |
Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage Nature Communications |
author_facet |
Nam Soo Lee Hee Jin Chung Hyoung-June Kim Seo Yun Lee Jae-Hoon Ji Yoojeong Seo Seung Hun Han Minji Choi Miyong Yun Seok-Geun Lee Kyungjae Myung Yonghwan Kim Ho Chul Kang Hongtae Kim |
author_sort |
Nam Soo Lee |
title |
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage |
title_short |
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage |
title_full |
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage |
title_fullStr |
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage |
title_full_unstemmed |
TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage |
title_sort |
traip/rnf206 is required for recruitment of rap80 to sites of dna damage |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2016-01-01 |
description |
Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination. |
url |
https://doi.org/10.1038/ncomms10463 |
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