Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation
Enteropathy-associated T-cell lymphoma (EATL) is a rare disease that accounts for not more than 1.4% of all lymphomas. It is most common in Europe, followed by North America and Asia. The disease is associated with gluten-sensitive celiac disease in 50% of cases and divided into types I and II. Mean...
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"Consilium Medicum" Publishing house
2013-07-01
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Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31328 |
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doaj-72c40e461a034b68ae8016abd90e22832020-11-25T03:06:08Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-07-01857798328344Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantationV I Vorob'evS K KravchenkoA M KovriginaEnteropathy-associated T-cell lymphoma (EATL) is a rare disease that accounts for not more than 1.4% of all lymphomas. It is most common in Europe, followed by North America and Asia. The disease is associated with gluten-sensitive celiac disease in 50% of cases and divided into types I and II. Mean-dose CHOP-like therapy is ineffective, with a median overall survival of 7-10 months. With high-dose therapy, 5-year survival rates can be 60%, but it can be used in not more than half of the cases. This is associated with the serious somatic status of most patients at diagnosis and with a median age of 57-64 years. The article presents a literature review and a case of successful therapy in a 58-year-old patient with type I EATL using the mNHL-BFM-90 protocol and autologous hematopoietic stem cell transplantation.https://ter-arkhiv.ru/0040-3660/article/view/31328enteropathy-associated t-cell lymphomaceliac diseasenhl-bfm-90autologous hematopoietic stem cell transplantationnhl-bfm-90 |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
V I Vorob'ev S K Kravchenko A M Kovrigina |
spellingShingle |
V I Vorob'ev S K Kravchenko A M Kovrigina Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation Терапевтический архив enteropathy-associated t-cell lymphoma celiac disease nhl-bfm-90 autologous hematopoietic stem cell transplantation nhl-bfm-90 |
author_facet |
V I Vorob'ev S K Kravchenko A M Kovrigina |
author_sort |
V I Vorob'ev |
title |
Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
title_short |
Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
title_full |
Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
title_fullStr |
Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
title_full_unstemmed |
Successful therapy for enteropathy-associated peripheral T-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
title_sort |
successful therapy for enteropathy-associated peripheral t-cell lymphoma using high-dose polychemotherapy and autologous hematopoietic stem cell transplantation |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2013-07-01 |
description |
Enteropathy-associated T-cell lymphoma (EATL) is a rare disease that accounts for not more than 1.4% of all lymphomas. It is most common in Europe, followed by North America and Asia. The disease is associated with gluten-sensitive celiac disease in 50% of cases and divided into types I and II. Mean-dose CHOP-like therapy is ineffective, with a median overall survival of 7-10 months. With high-dose therapy, 5-year survival rates can be 60%, but it can be used in not more than half of the cases. This is associated with the serious somatic status of most patients at diagnosis and with a median age of 57-64 years. The article presents a literature review and a case of successful therapy in a 58-year-old patient with type I EATL using the mNHL-BFM-90 protocol and autologous hematopoietic stem cell transplantation. |
topic |
enteropathy-associated t-cell lymphoma celiac disease nhl-bfm-90 autologous hematopoietic stem cell transplantation nhl-bfm-90 |
url |
https://ter-arkhiv.ru/0040-3660/article/view/31328 |
work_keys_str_mv |
AT vivorobev successfultherapyforenteropathyassociatedperipheraltcelllymphomausinghighdosepolychemotherapyandautologoushematopoieticstemcelltransplantation AT skkravchenko successfultherapyforenteropathyassociatedperipheraltcelllymphomausinghighdosepolychemotherapyandautologoushematopoieticstemcelltransplantation AT amkovrigina successfultherapyforenteropathyassociatedperipheraltcelllymphomausinghighdosepolychemotherapyandautologoushematopoieticstemcelltransplantation |
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