Aptamers in Bordeaux, 24–25 June 2016
The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemic...
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MDPI AG
2017-01-01
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| Series: | Pharmaceuticals |
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| Online Access: | http://www.mdpi.com/1424-8247/10/1/14 |
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doaj-72dcd0f4a83d4416a3067b639cdd6f302020-11-25T03:23:09ZengMDPI AGPharmaceuticals1424-82472017-01-011011410.3390/ph10010014ph10010014Aptamers in Bordeaux, 24–25 June 2016Jean-Jacques Toulmé0Paloma H. Giangrande1Günter Mayer2Beatrix Suess3Frédéric Ducongé4Bruce Sullenger5Vittorio de Franciscis6Fabien Darfeuille7Eric Peyrin8ARNA Laboratory, Inserm U1212, CNRS UMR5320, University of Bordeaux, Bordeaux 33076, FranceDepartment of Internal Medicine, University of Iowa, Iowa City, IA 52242, USAUnit Chemical Biology and Medicinal Chemistry, University of Bonn, Bonn 53121, GermanyDepartment of Biology, Technical University Darmstadt, Darmstadt 64287, GermanyCEA, DRF, I2BM, MIRCen, CNRS UMR 9199, University Paris Saclay, Fontenay aux Roses 92265, FranceDepartment of Surgery, Duke University, Durham, NC 27710, USAInstitute of Experimental Endocrinology and Oncology, CNR, Naples 80145, ItalyARNA Laboratory, Inserm U1212, CNRS UMR5320, University of Bordeaux, Bordeaux 33076, FranceDepartment of Molecular Pharmacochemistry, CNRS UMR5063, University Grenoble Alpes, Saint Martin d’Hères 38400, FranceThe symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemically modified nucleic acid bases that provide aptamers with new properties were presented. The power of aptamer platforms for multiplex analysis of biomarkers of major human diseases was described. The potential of aptamers for the treatment of cancer or cardiovascular diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. A second edition of “Aptamers in Bordeaux” will take place on September 2017 (http://www.aptamers-in-bordeaux.com/).http://www.mdpi.com/1424-8247/10/1/14aptamerin vitro selectionSELEXriboswitcholigonucleotidebiosensorcardiovascularcancercell-targeted aptamersimagingsynthetic biology |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jean-Jacques Toulmé Paloma H. Giangrande Günter Mayer Beatrix Suess Frédéric Ducongé Bruce Sullenger Vittorio de Franciscis Fabien Darfeuille Eric Peyrin |
| spellingShingle |
Jean-Jacques Toulmé Paloma H. Giangrande Günter Mayer Beatrix Suess Frédéric Ducongé Bruce Sullenger Vittorio de Franciscis Fabien Darfeuille Eric Peyrin Aptamers in Bordeaux, 24–25 June 2016 Pharmaceuticals aptamer in vitro selection SELEX riboswitch oligonucleotide biosensor cardiovascular cancer cell-targeted aptamers imaging synthetic biology |
| author_facet |
Jean-Jacques Toulmé Paloma H. Giangrande Günter Mayer Beatrix Suess Frédéric Ducongé Bruce Sullenger Vittorio de Franciscis Fabien Darfeuille Eric Peyrin |
| author_sort |
Jean-Jacques Toulmé |
| title |
Aptamers in Bordeaux, 24–25 June 2016 |
| title_short |
Aptamers in Bordeaux, 24–25 June 2016 |
| title_full |
Aptamers in Bordeaux, 24–25 June 2016 |
| title_fullStr |
Aptamers in Bordeaux, 24–25 June 2016 |
| title_full_unstemmed |
Aptamers in Bordeaux, 24–25 June 2016 |
| title_sort |
aptamers in bordeaux, 24–25 june 2016 |
| publisher |
MDPI AG |
| series |
Pharmaceuticals |
| issn |
1424-8247 |
| publishDate |
2017-01-01 |
| description |
The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemically modified nucleic acid bases that provide aptamers with new properties were presented. The power of aptamer platforms for multiplex analysis of biomarkers of major human diseases was described. The potential of aptamers for the treatment of cancer or cardiovascular diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. A second edition of “Aptamers in Bordeaux” will take place on September 2017 (http://www.aptamers-in-bordeaux.com/). |
| topic |
aptamer in vitro selection SELEX riboswitch oligonucleotide biosensor cardiovascular cancer cell-targeted aptamers imaging synthetic biology |
| url |
http://www.mdpi.com/1424-8247/10/1/14 |
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