Urokinase Gene 3′-UTR T/C Polymorphism Is Associated with Malignancy and ESRD in Idiopathic Membranous Nephropathy

Idiopathic membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in adults, and 25% of MN patients proceed to ESRD. Urokinase plasminogen activator (uPA) may play an important role in reducing renal fibrosis. This study was conducted to clarify the relationship between u...

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Bibliographic Details
Main Authors: Cheng-Hsu Chen, Shih-Yin Chen, Kuo-Hsiung Shu, Mei-Chin Wen, Chi-Hung Cheng, Ming-Ju Wu, Tung-Min Yu, Ya-Wen Chuang, Fuu-Jen Tsai
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/425095