Cetuximab-Induced MET Activation Acts as a Novel Resistance Mechanism in Colon Cancer Cells

Cetuximab-Induced MET Activation Acts as a Novel Resistance Mechanism in Colon Cancer Cells

Aberrant MET expression and hepatocyte growth factor (HGF) signaling are implicated in promoting resistance to targeted agents; however, the induced MET activation by epidermal growth factor receptor (EGFR) inhibitors mediating resistance to targeted therapy remains elusive. In this study, we identi...

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Bibliographic Details
Main Authors: Na Song, Shizhou Liu, Jingdong Zhang, Jing Liu, Ling Xu, Yunpeng Liu, Xiujuan Qu
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
cetuximab
MET
EGFR
SRC
colon cancer
Online Access:http://www.mdpi.com/1422-0067/15/4/5838

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