Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points
We present the case of a patient with a nonbacterial thrombotic aortic valve endocarditis experiencing severe thromboembolic complications and an acute right internal carotid artery occlusion in the context of a paraneoplastic syndrome and an asymptomatic severe acute respiratory syndrome coronaviru...
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doaj-72e638ada9cf4a3885a8b9e63f20c1072021-02-13T04:26:25ZengElsevierCJC Open2589-790X2021-02-0132217220Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching PointsNorman Mangner, MD0Krunoslav Sveric, MD1Johannes C. Gerber, MD2Jan Svitil, MD3Axel Linke, MD4Stefanie Jellinghaus, MD5Herzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, Germany; Corresponding author: Dr Norman Mangner, Herzzentrum Dresden—Technische Universität Dresden, Department of Internal Medicine and Cardiology, Fetscherstr. 76, 01307 Dresden, Germany. Tel: +1-49-351-45025297; fax: +1-49-351-4501702.Herzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, GermanyNeuroradiology, Dresden Neurovascular Center, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyHerzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, GermanyHerzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, GermanyHerzzentrum Dresden, Technische Universität Dresden, Department of Internal Medicine and Cardiology, Dresden, GermanyWe present the case of a patient with a nonbacterial thrombotic aortic valve endocarditis experiencing severe thromboembolic complications and an acute right internal carotid artery occlusion in the context of a paraneoplastic syndrome and an asymptomatic severe acute respiratory syndrome coronavirus-2 infection, despite treatment with different and overlapping anticoagulant medications. Patients with increased thrombogenicity due to an underlying disease might be at increased risk for thrombotic events during a severe acute respiratory syndrome coronavirus-2 infection. Résumé: Nous présentons le cas d’un patient atteint d’endocardite thrombotique non bactérienne de la valve aortique et présentant des complications thromboemboliques graves et une occlusion aiguë de la carotide interne droite dans le contexte d’un syndrome paranéoplasique et d’une infection à coronavirus du syndrome respiratoire aigu sévère 2 (SRAS-CoV-2) asymptomatique, malgré différentes anticoagulothérapies se chevauchant. Les patients présentant une thrombogénicité accrue en raison d’une affection sous-jacente pourraient courir un plus grand risque d’événement thrombotique en cas d’infection à SRAS-CoV-2.http://www.sciencedirect.com/science/article/pii/S2589790X20301694 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Norman Mangner, MD Krunoslav Sveric, MD Johannes C. Gerber, MD Jan Svitil, MD Axel Linke, MD Stefanie Jellinghaus, MD |
spellingShingle |
Norman Mangner, MD Krunoslav Sveric, MD Johannes C. Gerber, MD Jan Svitil, MD Axel Linke, MD Stefanie Jellinghaus, MD Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points CJC Open |
author_facet |
Norman Mangner, MD Krunoslav Sveric, MD Johannes C. Gerber, MD Jan Svitil, MD Axel Linke, MD Stefanie Jellinghaus, MD |
author_sort |
Norman Mangner, MD |
title |
Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points |
title_short |
Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points |
title_full |
Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points |
title_fullStr |
Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points |
title_full_unstemmed |
Paraneoplastic Syndrome and SARS-CoV-2—Incremental Effect of 2 Thrombogenic Conditions?Novel Teaching Points |
title_sort |
paraneoplastic syndrome and sars-cov-2—incremental effect of 2 thrombogenic conditions?novel teaching points |
publisher |
Elsevier |
series |
CJC Open |
issn |
2589-790X |
publishDate |
2021-02-01 |
description |
We present the case of a patient with a nonbacterial thrombotic aortic valve endocarditis experiencing severe thromboembolic complications and an acute right internal carotid artery occlusion in the context of a paraneoplastic syndrome and an asymptomatic severe acute respiratory syndrome coronavirus-2 infection, despite treatment with different and overlapping anticoagulant medications. Patients with increased thrombogenicity due to an underlying disease might be at increased risk for thrombotic events during a severe acute respiratory syndrome coronavirus-2 infection. Résumé: Nous présentons le cas d’un patient atteint d’endocardite thrombotique non bactérienne de la valve aortique et présentant des complications thromboemboliques graves et une occlusion aiguë de la carotide interne droite dans le contexte d’un syndrome paranéoplasique et d’une infection à coronavirus du syndrome respiratoire aigu sévère 2 (SRAS-CoV-2) asymptomatique, malgré différentes anticoagulothérapies se chevauchant. Les patients présentant une thrombogénicité accrue en raison d’une affection sous-jacente pourraient courir un plus grand risque d’événement thrombotique en cas d’infection à SRAS-CoV-2. |
url |
http://www.sciencedirect.com/science/article/pii/S2589790X20301694 |
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