Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo
Enhancers constitute one of the major components of regulatory machinery of metazoans. Although several genome-wide studies have focused on finding and locating enhancers in the genomes, the fundamental principles governing their internal architecture and cis-regulatory grammar remain elusive. Here,...
Main Authors: | Rupinder Sayal, Jacqueline M Dresch, Irina Pushel, Benjamin R Taylor, David N Arnosti |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-05-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/08445 |
Similar Items
-
Enhancing Ebony? Common Associations With a cis-Regulatory Haplotype for Drosophila melanogaster Thoracic Pigmentation in a Japanese Population and Australian Populations
by: Marina Telonis-Scott, et al.
Published: (2018-07-01) -
In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system
by: Lori Glenwinkel, et al.
Published: (2021-06-01) -
Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes
by: Stevephen Hung, et al.
Published: (2019-02-01) -
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function
by: Mary Lauren Benton, et al.
Published: (2019-06-01) -
Genome-wide prediction of cis-regulatory regions using supervised deep learning methods
by: Yifeng Li, et al.
Published: (2018-05-01)