Parishin C Attenuates Phencyclidine-Induced Schizophrenia-Like Psychosis in Mice: Involvements of 5-HT1A Receptor
Parishin C, a major component of Gastrodia elata BLUME (GE), was purified from GE. Because GE modulates the serotonergic system and the 5-HT1A receptor is an important therapeutic target of schizophrenia, we examined whether parishin C affects phencyclidine-induced abnormal behaviors in mice. Phency...
Main Authors: | Eun-Joo Shin, Wan Kyunn Whang, Sungun Kim, Jae-Hyung Bach, Jin-Man Kim, Xuan-Khanh Thi Nguyen, Thuy-Ty Lan Nguyen, Bae Dong Jung, Kiyofumi Yamada, Toshitaka Nabeshima, Hyoung-Chun Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2010-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319309089 |
Similar Items
-
Extraction and purification of parishin from Gastrodia eleta blume
by: Ru-Yin Wu, et al.
Published: (2009) -
Brain-Derived Neurotrophic Factor/TrkB Signaling in Memory Processes
by: Kiyofumi Yamada, et al.
Published: (2003-01-01) -
Artemisia iwayomogi Extract Attenuates High-Fat Diet-Induced Obesity by Decreasing the Expression of Genes Associated with Adipogenesis in Mice
by: Yeji Choi, et al.
Published: (2013-01-01) -
Clozapine Prevents a Decrease in Neurogenesis in Mice Repeatedly Treated With Phencyclidine
by: Kenji Maeda, et al.
Published: (2007-01-01) -
Myocardial protection properties of parishins from the roots of Gastrodia elata Bl
by: Qi Wang, et al.
Published: (2020-01-01)