Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment
Abstract Objective: To assess trends and predictors of the glomerular filtration rate (GFR) after renal mass cryoablation in patients with and without history of renal impairment. Materials and Methods: This was a retrospective study of 39 patients who underwent computed tomography-guided percutan...
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doaj-73005dfb71c742648a5e7fc80c77d83d2020-11-25T02:52:33ZengColégio Brasileiro de Radiologia e Diagnóstico por ImagemRadiologia Brasileira0100-39841678-709953314114710.1590/0100-3984.2019.0098S0100-39842020000300004Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairmentPedro V. StaziakiHarshna V. VadvalaVanessa Fiorini FurtadoDania DayeRonald S. ArellanoRaul N. UppotAbstract Objective: To assess trends and predictors of the glomerular filtration rate (GFR) after renal mass cryoablation in patients with and without history of renal impairment. Materials and Methods: This was a retrospective study of 39 patients who underwent computed tomography-guided percutaneous cryoablation of a renal mass, divided into two groups: those with prior renal impairment (PRI+); and those without prior renal impairment (PRI−). The GFR trend and the chronic kidney disease stage were evaluated at baseline, as well as at 1, 6, and 12 months after cryoablation. Predictors of GFR at 1 and 6 months were modeled with linear regression. Results: In both groups, the mean GFR at 1 month and 6 months was significantly lower than at baseline (p < 0.001 and p = 0.01, respectively). Although the GFR was lower across all time points in the PRI+ group (−26.1; p < 0.001), the overall trend was not statistically different from that observed in the PRI− group (p = 0.89). Univariate analysis showed that the decline in GFR at 1 and 6 months correlated with the baseline GFR (0.77 and 0.63; p < 0.001 and p = 0.03, respectively) and with the size of the ablation zone (−7.6 and −12.84, respectively; p = 0.03 for both). However, in the multivariate model, baseline GFR was predictive only of GFR at 1 month (p < 0.001). Conclusion: The trend in GFR decline after cryoablation is similar for patients with and without a history of renal impairment. Baseline GFR predicts the mean GFR in the early post-cryoablation period.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000300004&lng=en&tlng=enradiologia intervencionistainsuficiência renalrim/fisiopatologiataxa de filtração glomerulartomografia computadorizada/métodos |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pedro V. Staziaki Harshna V. Vadvala Vanessa Fiorini Furtado Dania Daye Ronald S. Arellano Raul N. Uppot |
spellingShingle |
Pedro V. Staziaki Harshna V. Vadvala Vanessa Fiorini Furtado Dania Daye Ronald S. Arellano Raul N. Uppot Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment Radiologia Brasileira radiologia intervencionista insuficiência renal rim/fisiopatologia taxa de filtração glomerular tomografia computadorizada/métodos |
author_facet |
Pedro V. Staziaki Harshna V. Vadvala Vanessa Fiorini Furtado Dania Daye Ronald S. Arellano Raul N. Uppot |
author_sort |
Pedro V. Staziaki |
title |
Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
title_short |
Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
title_full |
Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
title_fullStr |
Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
title_full_unstemmed |
Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
title_sort |
early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment |
publisher |
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem |
series |
Radiologia Brasileira |
issn |
0100-3984 1678-7099 |
description |
Abstract Objective: To assess trends and predictors of the glomerular filtration rate (GFR) after renal mass cryoablation in patients with and without history of renal impairment. Materials and Methods: This was a retrospective study of 39 patients who underwent computed tomography-guided percutaneous cryoablation of a renal mass, divided into two groups: those with prior renal impairment (PRI+); and those without prior renal impairment (PRI−). The GFR trend and the chronic kidney disease stage were evaluated at baseline, as well as at 1, 6, and 12 months after cryoablation. Predictors of GFR at 1 and 6 months were modeled with linear regression. Results: In both groups, the mean GFR at 1 month and 6 months was significantly lower than at baseline (p < 0.001 and p = 0.01, respectively). Although the GFR was lower across all time points in the PRI+ group (−26.1; p < 0.001), the overall trend was not statistically different from that observed in the PRI− group (p = 0.89). Univariate analysis showed that the decline in GFR at 1 and 6 months correlated with the baseline GFR (0.77 and 0.63; p < 0.001 and p = 0.03, respectively) and with the size of the ablation zone (−7.6 and −12.84, respectively; p = 0.03 for both). However, in the multivariate model, baseline GFR was predictive only of GFR at 1 month (p < 0.001). Conclusion: The trend in GFR decline after cryoablation is similar for patients with and without a history of renal impairment. Baseline GFR predicts the mean GFR in the early post-cryoablation period. |
topic |
radiologia intervencionista insuficiência renal rim/fisiopatologia taxa de filtração glomerular tomografia computadorizada/métodos |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842020000300004&lng=en&tlng=en |
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